PROSPECTIVE STUDY OF EFFECTS OF TURP ON OUTCOME,MORBIDITY AND MORTALITY IN PATIENTS WITH NON DIALYSIS REQUIRING RENAL INSUFFICIENCY

Dr. Prashanth Adiga

Abstract


INTRODUCTION

Benign Prostate Hyperplasia is a common disease in adult men and its incidence is age related. Prevalence of BPH is approximately 25% in men aged 40 to 49 years, 50% in men aged 50 to 59 years and 80% in men aged 70 to 79 years. 1 Renal failure and symptomatic benign prostatic hyperplasia (BPH) are two common health problems, they usually co-exist in 5.9–13.6% of the male population over 50 years of age.

TURP remains the gold standard surgical procedure for treatment of these cases. However, patients in renal failure have an increased risk for complications after TURP compared with patients with normal renal function, so we wanted to study the treatment outcome and complications associated with its management.

The purpose of this study was to determine the incidence of renal failure associated with BPH , effect of TURP in the morbilidity and mortality of patients with renal failure.

MATERIALS AND METHODS

Prospective study from October 2017 to November 2019 Setting : Govt. Stanley Medical college and Hospital, Chennai, This is a clinical study of 80 cases of Benign prostatic hyperplasia in normal and in patients with non dialysis requiring renal failure who underwent

Results

Once the serum creatinine values stabilized, the readings were recorded. Out of 40 patients who presented with elevated renal parameters, (patient with s.creatinine more than 1.3mg/dl ) ten patients subsequently showed fall in serum creatinine below 1.3, hence were considered along with normal patients in group 1. Because of this, the subsequent serum creatinine values of rest of 30  patients stabilized at a mean of 1.7 with a standard deviation of 0.3. Interestingly patients whose serum creatinine which stabilized at a value of more than 1.3, some of them had coexistent diabetes, hypertension. This might be an explanation that these patients have developed preexisting renal disease which was worsened by their developing benign prostatic hyperplasia

in group 1, out of 30  patients, three people had bleeding, one had retention, one perioperative death due to myocardial infarction was recorded, one patient had infection.

In all the patients with bleeding as complication, blood transfusion was given. Whereas in group 2, two people had bleeding out of 40 patients studied. ( 8% compared to 20% in group 1).

CONCLUSION

The incidence of associated with benign prostatic hyperplasia in our study was about 12.5%. .


Keywords


Benign Prostate , TURP , renal failure

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References


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