Dr. Dilip Kumar Bhowmik, Dr. Mohammad Zakiuddin


BACKGROUND: Bupivacaine is an amide local anaesthetic used in hyperbaric and plain forms
administered as spinal anesthesia. It is the most commonly used local anaesthetic for spinal anesthesia
(SA). There are two forms of commercially available bupivacaine; isobaric bupivacaine (IB): a formulation with a specic
gravity or density equal to cerebro spinal uid and hyperbaric bupivacaine (HB): a formulation with density heavier than
cerebro spinal uid. It is widely believed that the choice between isobaric bupivacaine and hyperbaric bupivacaine
formulations alters the block characteristics for the conduct of surgery under spinal anesthesia.
AIMS AND OBJECTIVE: The aim of this study was to systematically review the comparative evidence regarding the
effectiveness and safety of the two formulations when used for spinal anesthesia for adult and to compare the use of isobaric
and hyperbaric bupivacaine during lower abdomen surgery and their outcome.
METHODS AND MATERIAL: Sixty patients who underwent lower abdominal, hips, and lower extremity surgeries were
randomized into two groups. Group I received 20


Isobaric bupivacaine, hyperbaric bupivacaine, spinal anesthesia.

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